The Roumeli Municipal Regional Theatre, based in Lamia, the only one in the Peripheral area of Sterea Ellada, it was incorporated into the network of the Rethymno Municipalities of the Prefecture of the Ministry of Culture in 1985. It was opened and started performances in the same year as Iakovos Campanelli's “The Backyard of Miracles”. Its foundation was already preceded by a decision made in 1983 by the Lamia Municipal Council meeting. From then until 1988 it was an autonomous Public Legal Entity of the Municipality. In 1988, the Roumeli Municipal Regional theatre became a state business of Lamia Municipality, in legal form in which it operated until April 2008, when it became a Municipal Welfare Fund of Lamia Council and as such operates until today.

The activity of Roumeli Municipal Regional theatre develops in three stages, the Central Stage, the Experimental Stage and the Children's Stage. On the Main Stage, Aeschylus, Euripides, Aristophanes, Shakespeare, Johnson, Moliere, Goldoni, Feydeau, Lorca, Miller and Williams have performed here, amongst others. Emphasis was also given to modern Greek theatre works by Campanelli, Kehaidi-Haviara, Skourti, Korre, Bost and others. On the Experimental Stage, amongst others, works by Ridley, LaBute, Dukofsky, Toma, Tsikliropoulos, Kovacevic, and others, have been performed here. Whilst on the Children's Stage, works of Aristophanes, Armeni, Tsianou, Triviza, Braoudaki, Kaloyeropoulou, Roungeri, Baum, Twain, Way, Garcia Lorca, Kenny and others.

Since 1998, every year Roumeli theatre organizes the Festival for soloists and actors by hosting single person performances.

Finally, within the framework of Roumeli, Municipal Regional theatre and with the support of the amateur dramatics, a Theatre Workshop operates as well as an Amateur Stage.

The Roumeli Municipal Regional theatre has toured all over Greece and has performed in Constantinople with performances of “Fiakas” by Miltiadis Hourmouzis, 2002, “Leprendis” by Miltiadis Hourmouzis 2005 at Ferikioi-ERTHO theatre in Cairo, Egypt (with the production of “Prominent Bound” by Aeschylus in Cairo Opera in 2009) and Edinburgh, Great Britain (with Philip Ridley's “Fairy tale for Two” in 2005 at the Edinburgh Fringe Festival).